The 2010 Toyota Tacoma is available as a 2-door, 3-seat regular side. Starting at $19,305, the 2010 Toyota Tacoma 4x4 Regular Cab is powered by a 2.7L , 4 -cylinder engine mated to a manual transmission that returns an EPA estimated 17-mpg in the city and 22-mpg on the highway. The top of the line 2010ToyotaTacomaX-Runner V6 (M6) 4x2 Access Cab , priced at $ 25,460 , is powered by a 4.0L , 6 - cylinder engine mated to a manual transmission that returns an EPA estimated 15-mpg in the city and 18-mpg on the highway.