The 2021 Toyota Sienna is available as a 4-door, 7-seat passenger van. Starting at $34,460, the 2021 Toyota Sienna LE 8 FWD is powered by a 2.5L, 4-cylinder engine mated to an automatic transmission that returns an EPA estimated 36-mpg in the city and 36-mpg on the highway. The top of the line 2021 Toyota Sienna XSE 7 AWD, priced at $42,760, is powered by a 2.5L, 4-cylinder engine mated to an automatic transmission that returns an EPA estimated 35-mpg in the city and 36-mpg on the highway.