The 2006 Toyota Sienna is available as a 4-door, 7-seat passenger van. Starting at $23,775, the 2006 Toyota Sienna CE FWD Passenger is powered by a 3.3L , 6 -cylinder engine mated to an automatic transmission that returns an EPA estimated 19-mpg in the city and 26-mpg on the highway. The top of the line 2006ToyotaSiennaFWD Cargo , priced at $ 00 , is powered by a 3.3L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 19-mpg in the city and 26-mpg on the highway.