The 2010 Toyota Highlander is available as a 4-door, 5-seat sport utility. Starting at $25,855, the 2010 Toyota Highlander Base (A6) FWD is powered by a 2.7L , 4 -cylinder engine mated to an automatic transmission that returns an EPA estimated 20-mpg in the city and 27-mpg on the highway. The top of the line 2010ToyotaHighlanderSE AWD , priced at $ 33,930 , is powered by a 3.5L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 17-mpg in the city and 23-mpg on the highway.