The 2016 Nissan Murano is available as a 4-door, 5-seat sport utility. Starting at $29,740, the 2016 Nissan Murano S FWD is powered by a 3.5L , 6 -cylinder engine mated to an automatic transmission that returns an EPA estimated 21-mpg in the city and 28-mpg on the highway. The top of the line 2016NissanMuranoPlatinum AWD , priced at $ 40,780 , is powered by a 3.5L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 21-mpg in the city and 28-mpg on the highway.