The 2016 Nissan Altima is available as a 4-door, 5-seat sedan. Starting at $22,500, the 2016 Nissan Altima 2.5 is powered by a 2.5L , 4 -cylinder engine mated to an automatic transmission that returns an EPA estimated 27-mpg in the city and 39-mpg on the highway. The top of the line 2016NissanAltima3.5 SL w/LED , priced at $ 32,690 , is powered by a 3.5L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 22-mpg in the city and 32-mpg on the highway.