The 2006 Nissan 350Z is available as a 2-door, 2-seat coupe. Starting at $27,650, the 2006 Nissan 350Z Base (M6) Coupe is powered by a 3.5L , 6 -cylinder engine mated to a manual transmission that returns an EPA estimated 19-mpg in the city and 25-mpg on the highway. The top of the line 2006Nissan350ZGrand Touring (A5) Roadster , priced at $ 41,000 , is powered by a 3.5L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 18-mpg in the city and 24-mpg on the highway.