The 2021 Mercedes-Benz Sprinter 3500 is available as a 3-door, 2-seat cargo van. Starting at $43,145, the 2021 Mercedes-Benz Sprinter 3500 I4 Sprinter 3500 RWD Cargo 144 WB HD is powered by a 2.0LL , 4 -cylinder engine mated to an automatic transmission that returns an EPA estimated The top of the line 2021Mercedes-BenzSprinter 3500V6 Sprinter 3500 RWD Crew 170 WB HD , priced at $ 54,840 , is powered by a 3.0LL , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated