The 2017 Mercedes-Benz S-Class is available as a 4-door, 5-seat sedan. Starting at $131,400, the 2017 Mercedes-Benz S-Class S 550 RWD Cabriolet is powered by a 4.7L, 8-cylinder engine mated to an automatic transmission that returns an EPA estimated 17-mpg in the city and 25-mpg on the highway. The top of the line 2017 Mercedes-Benz S-Class S 550 AWD 4MATIC Coupe, priced at $122,750, is powered by a 4.7L, 8-cylinder engine mated to an automatic transmission that returns an EPA estimated 17-mpg in the city and 25-mpg on the highway.