The 2010 Mercedes-Benz S-Class is available as a 4-door, 5-seat sedan. Starting at $87,950, the 2010 Mercedes-Benz S-Class S 400 Hybrid RWD Sedan is powered by a 3.5L , 6 -cylinder engine mated to an automatic transmission that returns an EPA estimated 19-mpg in the city and 25-mpg on the highway. The top of the line 2010Mercedes-BenzS-ClassS 550 AWD 4MATIC Sedan , priced at $ 94,600 , is powered by a 5.5L , 8 - cylinder engine mated to an automatic transmission that returns an EPA estimated 14-mpg in the city and 21-mpg on the highway.