The 2000 Mercedes-Benz S-Class is available as a 4-door, 5-seat sedan. Starting at $77,850, the 2000 Mercedes-Benz S-Class Base is powered by a 5.0L , 8 -cylinder engine mated to an automatic transmission that returns an EPA estimated 16-mpg in the city and 23-mpg on the highway. The top of the line 2000Mercedes-BenzS-ClassBase , priced at $ 69,700 , is powered by a 4.3L , 8 - cylinder engine mated to an automatic transmission that returns an EPA estimated 17-mpg in the city and 24-mpg on the highway.