The 2018 Mercedes-Benz GLE 350 is available as a 4-door, 5-seat sport utility. Starting at $54,700, the 2018 Mercedes-Benz GLE 350 GLE 350 AWD is powered by a 3.5L, 6-cylinder engine mated to an automatic transmission that returns an EPA estimated 18-mpg in the city and 22-mpg on the highway. The top of the line 2018 Mercedes-Benz GLE 350 GLE 350 4x2, priced at $52,200, is powered by a 3.5L, 6-cylinder engine mated to an automatic transmission that returns an EPA estimated 18-mpg in the city and 23-mpg on the highway.