The 2021 Mercedes-Benz E-Class is available as a 4-door, 5-seat sedan. Starting at $64,950, the 2021 Mercedes-Benz E-Class E 450 RWD Coupe is powered by a 3.0L , 6 -cylinder engine mated to an automatic transmission that returns an EPA estimated 23-mpg in the city and 31-mpg on the highway. The top of the line 2021Mercedes-BenzE-ClassE 450 AWD 4MATIC All-Terrain Wagon , priced at $ 67,600 , is powered by a 3.0L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 22-mpg in the city and 28-mpg on the highway.
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