The 2020 Mercedes-Benz AMG S 65 is available as a 4-door, 5-seat sedan. Starting at $235,600, the 2020 Mercedes-Benz AMG S 65 AMG S 65 RWD Sedan is powered by a 6.0L , 12 - cylinder engine mated to an automatic transmission that returns an EPA estimated 13-mpg in the city and 22-mpg on the highway.