The 2021 Mercedes-Benz AMG CLS 53 is available as a 4-door, 5-seat sedan. Starting at $81,550, the 2021 Mercedes-Benz AMG CLS 53 AMG CLS 53 Coupe AWD 4MATIC+ is powered by a 3.0L, 6-cylinder engine mated to an automatic transmission that returns an EPA estimated 21-mpg in the city and 26-mpg on the highway.