The 2018 Lexus RX 450hL is available as a 4-door, 7-seat sport utility. Starting at $50,620, the 2018 Lexus RX 450hL Premium is powered by a 3.5L, 6-cylinder engine mated to anautomatic transmission that returns an EPA estimated 29-mpg in the city and 28-mpg on the highway. The top of the line 2018 Lexus RX 450hL Luxury, priced at $54,555, is powered by a 3.5L, 6-cylinder engine mated to anautomatic transmission that returns an EPA estimated 29-mpg in the city and 28-mpg on the highway.