The 2008 Lexus RX 400h is available as a 4-door, 5-seat sport utility. Starting at $42,080, the 2008 Lexus RX 400h FWD is powered by a 3.3L, 6-cylinder engine mated to an automatic transmission that returns an EPA estimated 27-mpg in the city and 24-mpg on the highway. The top of the line 2008 Lexus RX 400h AWD, priced at $43,480, is powered by a 3.3L, 6-cylinder engine mated to an automatic transmission that returns an EPA estimated 26-mpg in the city and 24-mpg on the highway.