The 2022 Lexus LS 500 is available as a 4-door, 5-seat sedan. Starting at $76,100, the 2022 Lexus LS 500 Base RWD is powered by a 3.5LL , 6 -cylinder engine mated to an automatic transmission that returns an EPA estimated 18-mpg in the city and 29-mpg on the highway. The top of the line 2022LexusLS 500F SPORT AWD , priced at $ 82,950 , is powered by a 3.5LL , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 17-mpg in the city and 27-mpg on the highway.
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