The 2019 Lexus LS 500 is available as a 4-door, 5-seat sedan. Starting at $75,450, the 2019 Lexus LS 500 Base RWD is powered by a 3.5L, 6-cylinder engine mated to an automatic transmission that returns an EPA estimated 19-mpg in the city and 30-mpg on the highway. The top of the line 2019 Lexus LS 500 F Sport AWD, priced at $84,670, is powered by a 3.5L, 6-cylinder engine mated to an automatic transmission that returns an EPA estimated 18-mpg in the city and 27-mpg on the highway.