The 2016 Lexus LS 460 is available as a 4-door, 5-seat sedan. Starting at $72,520, the 2016 Lexus LS 460 RWD Sedan is powered by a 4.6L , 8 -cylinder engine that returns an EPA estimated 16-mpg in the city and 24-mpg on the highway. The top of the line 2016LexusLS 460AWD Long Wheelbase Sedan , priced at $ 82,305 , is powered by a 4.6L , 8 - cylinder engine that returns an EPA estimated 16-mpg in the city and 23-mpg on the highway.