The 2022 Lexus IS 500 is available as a 4-door, 5-seat sedan. Starting at $56,850, the 2022 Lexus IS 500 F SPORT Performance is powered by a 5.0LL , 8 -cylinder engine mated to an automatic transmission that returns an EPA estimated 17-mpg in the city and 25-mpg on the highway. The top of the line 2022LexusIS 500Premium , priced at $ 61,350 , is powered by a 5.0LL , 8 - cylinder engine mated to an automatic transmission that returns an EPA estimated 17-mpg in the city and 25-mpg on the highway.
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