The 2009 Lexus GS 350 is available as a 4-door, 5-seat sedan. Starting at $46,950, the 2009 Lexus GS 350 AWD is powered by a 3.5L , 6 -cylinder engine mated to an automatic transmission that returns an EPA estimated 18-mpg in the city and 25-mpg on the highway. The top of the line 2009LexusGS 350RWD , priced at $ 45,000 , is powered by a 3.5L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 19-mpg in the city and 26-mpg on the highway.