The 2021 Lexus ES 300h is available as a 4-door, 5-seat sedan. Starting at $41,910, the 2021 Lexus ES 300h Base is powered by a 2.5LL , 4 -cylinder engine mated to an automatic transmission that returns an EPA estimated 43-mpg in the city and 44-mpg on the highway. The top of the line 2021LexusES 300hUltra Luxury , priced at $ 50,910 , is powered by a 2.5LL , 4 - cylinder engine mated to an automatic transmission that returns an EPA estimated 43-mpg in the city and 44-mpg on the highway.