The 1999 Jeep Cherokee is available as a 2-door, 5-seat sport utility. Starting at $16,050, the 1999 Jeep Cherokee SE 4x2 2dr is powered by a 2.5L , 4 -cylinder engine mated to a manual transmission that returns an EPA estimated 21-mpg in the city and 25-mpg on the highway. The top of the line 1999JeepCherokeeRHD Rural Letter Carrier 4x4 4dr , priced at $ 22,655 , is powered by a 4.0L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 16-mpg in the city and 21-mpg on the highway.