The 2008 Isuzu Ascender is available as a 4-door, 5-seat sport utility. Starting at $27,149, the 2008 Isuzu Ascender 4x2 is powered by a 4.2L , 6 -cylinder engine mated to an automatic transmission that returns an EPA estimated 14-mpg in the city and 20-mpg on the highway. The top of the line 2008IsuzuAscender4x4 , priced at $ 29,149 , is powered by a 4.2L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 14-mpg in the city and 20-mpg on the highway.