The 2021 Honda Odyssey is available as a 4-door, 7-seat passenger van. Starting at $31,790, the 2021 Honda Odyssey LX is powered by a 3.5L, 6-cylinder engine mated to an automatic transmission that returns an EPA estimated 19-mpg in the city and 28-mpg on the highway. The top of the line 2021 Honda Odyssey Elite, priced at $47,820, is powered by a 3.5L, 6-cylinder engine mated to an automatic transmission that returns an EPA estimated 19-mpg in the city and 28-mpg on the highway.