The 2016 Honda Odyssey is available as a 4-door, 7-seat passenger van. Starting at $29,550, the 2016 Honda Odyssey LX is powered by a 3.5L , 6 -cylinder engine mated to an automatic transmission that returns an EPA estimated 19-mpg in the city and 28-mpg on the highway. The top of the line 2016HondaOdysseyTouring Elite , priced at $ 45,025 , is powered by a 3.5L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 19-mpg in the city and 28-mpg on the highway.