The 2012 Honda Odyssey is available as a 4-door, 7-seat passenger van. Starting at $28,375, the 2012 Honda Odyssey LX (A5) is powered by a 3.5L , 6 -cylinder engine mated to an automatic transmission that returns an EPA estimated 18-mpg in the city and 27-mpg on the highway. The top of the line 2012HondaOdysseyTouring Elite (A6) , priced at $ 43,825 , is powered by a 3.5L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 19-mpg in the city and 28-mpg on the highway.