The 2010 Honda Odyssey is available as a 4-door, 7-seat passenger van. Starting at $29,905, the 2010 Honda Odyssey EX is powered by a 3.5L , 6 -cylinder engine mated to an automatic transmission that returns an EPA estimated 16-mpg in the city and 23-mpg on the highway. The top of the line 2010HondaOdysseyTouring w/Rear Entertainment/Navi , priced at $ 40,755 , is powered by a 3.5L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 17-mpg in the city and 25-mpg on the highway.