The 2001 Honda Odyssey is available as a 4-door, 7-seat passenger van. Starting at $23,900, the 2001 Honda Odyssey LX is powered by a 3.5L , 6 -cylinder engine mated to an automatic transmission that returns an EPA estimated 18-mpg in the city and 25-mpg on the highway. The top of the line 2001HondaOdysseyEX With Navigation System , priced at $ 28,400 , is powered by a 3.5L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 18-mpg in the city and 25-mpg on the highway.