The 2001 GMC Safari is available as a 3-door, 2-seat cargo van. Starting at $23,441, the 2001 GMC Safari SLE RWD Passenger is powered by a 4.3L , 6 -cylinder engine mated to an automatic transmission that returns an EPA estimated 16-mpg in the city and 21-mpg on the highway. The top of the line 2001GMCSafariUpfitter AWD Cargo , priced at $ 24,250 , is powered by a 4.3L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 15-mpg in the city and 20-mpg on the highway.