The 2021 Ford F-350 is available as a 2-door, 3-seat regular side. Starting at $35,745, the 2021 Ford F-350 XL 4x2 SD Regular Cab is powered by a 6.2LL , 8 -cylinder engine mated to an automatic transmission that returns an EPA estimated The top of the line 2021FordF-350Limited 4x4 SD Crew Cab Long Box DRW , priced at $ 87,375 , is powered by a 6.7LL , 8 - cylinder engine mated to an automatic transmission that returns an EPA estimated