The 2010 Ford E-250 is available as a 3-door, 2-seat cargo van. Starting at $26,510, the 2010 Ford E-250 Commercial Cargo is powered by a 4.6L , 8 -cylinder engine mated to an automatic transmission that returns an EPA estimated The top of the line 2010FordE-250Recreational Extended Cargo , priced at $ 30,255 , is powered by a 4.6L , 8 - cylinder engine mated to an automatic transmission that returns an EPA estimated