The 2006 Cadillac Escalade is available as a 4-door, 7-seat sport utility. Starting at $53,850, the 2006 Cadillac Escalade 4x2 is powered by a 6.0L, 8-cylinder engine mated to an automatic transmission that returns an EPA estimated 14-mpg in the city and 18-mpg on the highway. The top of the line 2006 Cadillac Escalade AWD, priced at $56,405, is powered by a 6.0L, 8-cylinder engine mated to an automatic transmission that returns an EPA estimated 13-mpg in the city and 17-mpg on the highway.