The 2012 Cadillac CTS is available as a 4-door, 5-seat sedan. Starting at $35,915, the 2012 Cadillac CTS Base RWD Sedan is powered by a 3.0L , 6 -cylinder engine mated to a manual transmission that returns an EPA estimated 16-mpg in the city and 26-mpg on the highway. The top of the line 2012CadillacCTSPremium AWD Coupe , priced at $ 50,050 , is powered by a 3.6L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 18-mpg in the city and 27-mpg on the highway.