The 2022 Audi R8 is available as a 2-door, 2-seat coupe. Starting at $199,800, the 2022 Audi R8 quattro quattro Coupe is powered by a 5.2LL , 10 -cylinder engine mated to an automatic transmission that returns an EPA estimated 13-mpg in the city and 19-mpg on the highway. The top of the line 2022AudiR8RWD Spyder , priced at $ 160,900 , is powered by a 5.2LL , 10 - cylinder engine mated to an automatic transmission that returns an EPA estimated 14-mpg in the city and 23-mpg on the highway.