The 2022 Audi Q5 is available as a 4-door, 5-seat sport utility. Starting at $45,800, the 2022 Audi Q5 45 S line Premium is powered by a 2.0LL , 4 -cylinder engine mated to an automatic transmission that returns an EPA estimated 23-mpg in the city and 28-mpg on the highway. The top of the line 2022AudiQ540 , priced at $ 43,300 , is powered by a 2.0LL , 4 - cylinder engine mated to an automatic transmission that returns an EPA estimated 23-mpg in the city and 29-mpg on the highway.