The 2022 Audi A4 is available as a 4-door, 5-seat sedan. Starting at $39,900, the 2022 Audi A4 40 is powered by a 2.0LL , 4 -cylinder engine mated to an automatic transmission that returns an EPA estimated 26-mpg in the city and 34-mpg on the highway. The top of the line 2022AudiA445 S line , priced at $ 42,000 , is powered by a 2.0LL , 4 - cylinder engine mated to an automatic transmission that returns an EPA estimated 24-mpg in the city and 31-mpg on the highway.