The 2021 Acura TLX is available as a 4-door, 5-seat sedan. Starting at $37,500, the 2021 Acura TLX Base FWD Sedan is powered by a 2.0LL , 4 -cylinder engine mated to an automatic transmission that returns an EPA estimated 22-mpg in the city and 31-mpg on the highway. The top of the line 2021AcuraTLXType S w/Performance Tire AWD SH-AWD Sedan , priced at $ 53,100 , is powered by a 3.0LL , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 19-mpg in the city and 24-mpg on the highway.