The 2006 Acura MDX is available as a 4-door, 7-seat sport utility. Starting at $37,125, the 2006 Acura MDX Base is powered by a 3.5L , 6 -cylinder engine mated to an automatic transmission that returns an EPA estimated 17-mpg in the city and 23-mpg on the highway. The top of the line 2006AcuraMDXw/Touring/RES/Navi/Onstar , priced at $ 44,200 , is powered by a 3.5L , 6 - cylinder engine mated to an automatic transmission that returns an EPA estimated 17-mpg in the city and 23-mpg on the highway.